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Combined effects of temperature, irradiance and pH on Teleaulax amphioxeia (Cryptophyceae) physiology and feeding ratio for its predator Mesodinium rubrum (Ciliophora) ArchiMer
Gaillard, Sylvain; Charrier, Aurelie; Malo, Florent; Carpentier, Liliane; Bougaran, Gael; Hégaret, Helene; Réveillon, Damien; Hess, Philipp; Séchet, Veronique.
The cryptophyte Teleaulax amphioxeia is a source of plastids for the ciliate Mesodinium rubrum and both organisms are members of the trophic chain of several species of Dinophysis. It is important to better understand the ecology of organisms at the first trophic levels before assessing the impact of principal factors of global change on Dinophysis spp. Therefore, combined effects of temperature, irradiance and pH on growth rate, photosynthetic activity and pigment content of a temperate strain of T. amphioxeia were studied using a full factorial design (central composite design 23*) in 17 individually controlled bioreactors. The derived model predicted an optimal growth rate of T. amphioxeia at a light intensity of 400 µmol photons · m‐2 · s‐1, more...
Tipo: Text Palavras-chave: Dinophysis; Ecophysiology; Full factorial design; Global change; Mesodinium rubrum; Teleaulax amphioxeia.
Ano: 2020 URL: https://archimer.ifremer.fr/doc/00609/72155/70910.pdf
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Design, preparation and in vitro characterizations of fluconazole loaded nanostructured lipid carriers BJPS
Fernandes,Amanda Velinna; Pydi,Chinna Raja; Verma,Ruchi; Jose,Jobin; Kumar,Lalit.
Present study was aimed to prepare and characterize fluconazole loaded nanostructured lipid carriers (FLZ-NLCs) for the treatment of fungal infections. Fungal infections are tremendously widespread and are the often faced dermatological condition worldwide. FLZ-NLCs was prepared by ultrasonication emulsion technique using stearic acid (SA) as solid lipid, castor oil as liquid lipid and tween 20 as a surfactant. The mean diameter of optimized FLZ-NLCs were found to be 359.15 ± 9.83 nm. The drug content and entrapment efficiency of NLCs was found to be 102.97 ± 7.45% and 87 ± 0.59%, respectively. In vitro drug release studies of FLZ-NLCs showed 37.34 ± 2.08% drug release over a period of 72 h. The above studies confirmed the prepared FLZ-NLCs may be useful...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fluconazole; NLCs; Nanostructured lipid carriers; Fungal infections; Full factorial design; Design of experiment.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100524
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